ea0014p586 | (1) | ECE2007
Oláh Márk
, Szepesi Zsuzsanna
, Bodnár Ibolya
, Nagy György M.
, Tidrenczel Zsolt
It is well known that hypophyseotrophic dopamine (DA) exhibits a tonic inhibitory effect on pituitary lactotrops in vivo. We have previously observed that prolactin (PRL) cells obtained from lactating rats become partially resistant to DA following a brief suckling period compared to non-suckled control female rats. This, so-called desensitization (and a parallel appearance of tolerance) to DA is mediated through by a selective change of protein phospha...